The Clue
Ad Council output, for short (3 letter answer)
The Answer
PSA
Tags
Notes
The answer PSA is uncommon, appearing about once every 450 puzzles.
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Definition
PSA as a noun:
1. (prostate specific antigen, PSA) = a protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer