Enter a clue or pattern or both:

The Clue

Chicago Museum of Science and ___ (8 letter answer)

The Answer

INDUSTRY

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Notes

The answer INDUSTRY is so rare that it appears less than once every 2500 puzzles.

Definition

INDUSTRY as a noun:

1. the people or companies engaged in a particular kind of commercial enterprise; "each industry has its own trade publications"
2. (industry, manufacture) = the organized action of making of goods and services for sale; "American industry is making increased use of computers to control production"
3. (diligence, industriousness, industry) = persevering determination to perform a task; "his diligence won him quick promotions"; "frugality and industry are still regarded as virtues"