The Clue
Defense means, briefly (4 letter answer)
The Answer
ABMS
Tags
Notes
The answer ABMS is rarely seen, appearing only about once every 1300 puzzles.
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Definition
ABM as a noun:
1. (antiballistic missile, ABM) = a defensive missile designed to shoot down incoming intercontinental ballistic missiles; "the Strategic Arms Limitation Talks placed limits on the deployment of ABMs"