The Clue
Lou Gehrig's disease, for short (3 letter answer)
The Answer
ALS
Tags
Notes
The answer ALS is seen frequently, appearing about once every 90 puzzles.
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Definition
ALS as a noun:
1. (amyotrophic lateral sclerosis, ALS, Lou Gehrig's disease) = thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs
AL as a noun:
1. (aluminum, aluminium, Al, atomic number 13) = a silvery ductile metallic element found primarily in bauxite
2. (Alabama, Heart of Dixie, Camellia State, AL) = a state in the southeastern United States on the Gulf of Mexico; one of the Confederate states during the American Civil War