Enter a clue or pattern or both:
The Clue
Made hostile (10 letter answer)
The Answer
EMBITTERED
Tags
Notes
The answer EMBITTERED is so rare that it appears less than once every 2500 puzzles.
Definition
EMBITTER as a verb:
1. (embitter, envenom, acerbate) = cause to be bitter or resentful; "These injustices embittered her even more"