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The Clue

Matter of course (8 letter answer)

The Answer

SYLLABUS

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Notes

The answer SYLLABUS is so rare that it appears less than once every 2500 puzzles.

Definition

SYLLABUS as a noun:

1. (course of study, program, programme, curriculum, syllabus) = an integrated course of academic studies; "he was admitted to a new program at the university"