The Clue
Most pernicious (9 letter answer)
The Answer
DEADLIEST
Tags
Notes
The answer DEADLIEST is so rare that it appears less than once every 2500 puzzles.
Definition
DEADLY as an adjective:
1. (deadly, deathly, mortal) = causing or capable of causing death; "a fatal accident"; "a deadly enemy"; "mortal combat"; "a mortal illness"
2. (deadly, lethal) = of an instrument of certain death; "deadly poisons"; "lethal weapon"; "a lethal injection"
3. (deadly, venomous, virulent) = extremely poisonous or injurious; producing venom; "venomous snakes"; "a virulent insect bite"
4. (deadly, mortal) = involving loss of divine grace or spiritual death; "the seven deadly sins"
5. (baneful, deadly, pernicious, pestilent) = exceedingly harmful
6. (of a disease) having a rapid course and violent effect