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The Clue

Notwithstanding (7 letter answer)

The Answer

DESPITE

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Notes

The answer DESPITE is rarely seen, appearing only about once every 1200 puzzles.

Related Clues

In the face of
Insult
Regardless of

Definition

DESPITE as a noun:

1. (contempt, disdain, scorn, despite) = lack of respect accompanied by a feeling of intense dislike; "he was held in contempt"; "the despite in which outsiders were held is legendary"
2. contemptuous disregard; "she wanted neither favor nor despite"