Enter a clue or pattern or both:
The Clue
One struggling (7 letter answer)
The Answer
AGONIST
Tags
Notes
The answer AGONIST is so rare that it appears less than once every 2500 puzzles.
Related Clues
Competitor or contestant
Person in a conflict
Definition
AGONIST as a noun:
1. (protagonist, agonist) = the principal character in a work of fiction
2. someone involved in a contest or battle (as in an agon)
3. a muscle that contracts while another relaxes; "when bending the elbow the biceps are the agonist"
4. (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction