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The Clue

Outermost cell layer (8 letter answer)

The Answer

ECTODERM

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Notes

The answer ECTODERM is so rare that it appears less than once every 2500 puzzles.

Related Clues

Outer membrane of a jellyfish

Definition

ECTODERM as a noun:

1. (ectoderm, exoderm, ectoblast) = the outer germ layer that develops into skin and nervous tissue