The Clue
Pain of a sort (4 letter answer)
The Answer
PEST
Tags
Notes
The answer PEST is seen frequently, appearing about once every 90 puzzles.
Related Clues
Annoyance
Annoying one
Bothersome one
Buttinsky
Gadfly
Noodge
Nudge
Nudnik
Nuisance
Obnoxious one
Plague
Teaser
Tiresome one
Aphid, e.g.
Bothersome individual
Buttinsky, e.g.
DDT target
Exterminator's target
Fly, e.g.
Gnat or brat
Gnat, e.g.
Hanger-on, maybe
Lapel clutcher
Mole, e.g.
Mole, to a gardener
Mosquito, e.g.
Pain in the neck
Persistent annoyer
Real pill
Slug, e.g.
Slug, say
Termite, e.g.
Tick, e.g.
Unwelcome guest
Aphid, to a fruit tree
Gnat, rat or brat
Heckler or lapel grabber
Little brother, maybe
Definition
PEST as a noun:
1. (plague, pestilence, pest, pestis) = a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal
2. (plague, pestilence, pest) = any epidemic disease with a high death rate
3. (pest, blighter, cuss, pesterer, gadfly) = a persistently annoying person
4. any unwanted and destructive insect or other animal that attacks food or crops or livestock etc.; "he sprayed the garden to get rid of pests"; "many pests have developed resistance to the common pesticides"