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The ClueProper (6 letter answer)
NotesThe answer SEDATE is common and appears about once every 225 puzzles.
Tranquilize or tranquil
DefinitionSEDATE as a verb:
1. (sedate, calm, tranquilize, tranquillize, tranquillise) = cause to be calm or quiet as by administering a sedative to; "The patient must be sedated before the operation"
SEDATE as an adjective:
1. (sedate, staid) = characterized by dignity and propriety
2. (grave, sedate, sober, solemn) = dignified and somber in manner or character and committed to keeping promises; "a grave God-fearing man"; "a quiet sedate nature"; "as sober as a judge"; "a solemn promise"; "the judge was solemn as he pronounced sentence"