The Clue
Shakespeare's tamed shrew (11 letter answer)
The Answer
DOMESTICATE
Tags
Notes
The answer DOMESTICATE is so rare that it appears less than once every 2500 puzzles.
Definition
DOMESTICATE as a verb:
1. (domesticate, cultivate, naturalize, naturalise, tame) = adapt (a wild plant or unclaimed land) to the environment; "domesticate oats"; "tame the soil"
2. (domesticate, domesticize, domesticise, reclaim, tame) = overcome the wildness of; make docile and tractable; "He tames lions for the circus"; "reclaim falcons"
3. (domesticate, tame) = make fit for cultivation, domestic life, and service to humans; "The horse was domesticated a long time ago"; "The wolf was tamed and evolved into the house dog"