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The Clue

Soprano roles in operas by Cherubini and Giordano (6 letter answer)

The Answer

ELISAS

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Notes

The answer ELISAS is so rare that it appears less than once every 2500 puzzles.

Definition

ELISA as a noun:

1. (enzyme-linked-immunosorbent serologic assay, ELISA) = an assay that relies on an enzymatic conversion reaction and is used to detect the presence of specific substances (such as enzymes or viruses or antibodies or bacteria)