Enter a clue or pattern or both:
The Clue
Tight end, at times (7 letter answer)
The Answer
BLOCKER
Tags
Notes
The answer BLOCKER is so rare that it appears less than once every 2500 puzzles.
Definition
BLOCKER as a noun:
1. a football player whose responsibility is to block players attempting to stop an offensive play
2. (blocker, blocking agent) = a class of drugs that inhibit (block) some biological process