Enter a clue or pattern or both:
The Clue
Vexatious problem (8 letter answer)
The Answer
HEADACHE
Tags
Notes
The answer HEADACHE is rarely seen, appearing only about once every 1600 puzzles.
Related Clues
Cephalalgia
Problem
Worry
Annoying problem
Big bother
Ibuprofen target
Major annoyance
Annoying person or situation
Definition
HEADACHE as a noun:
1. (concern, worry, headache, vexation) = something or someone that causes anxiety; a source of unhappiness; "New York traffic is a constant concern"; "it's a major worry"
2. (headache, head ache, cephalalgia) = pain in the head caused by dilation of cerebral arteries or muscle contractions or a reaction to drugs