The Clue
___-aller (last resort) (3 letter answer)
The Answer
PIS
Tags
Notes
The answer PIS is uncommon, appearing about once every 375 puzzles.
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Mathematical constants
Ratio symbols
___-aller (last resort)
Circumference-figuring figures
Magnum and others: Abbr.
Magnum and others, for short
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Definition
PI as a noun:
1. the ratio of the circumference to the diameter of a circle; approximately equal to 3.14159265358979323846...
2. (private detective, PI, private eye, private investigator, operative, shamus, sherlock) = someone who can be employed as a detective to collect information
3. (principal investigator, PI) = the scientist in charge of an experiment or research project
4. the 16th letter of the Greek alphabet
5. (protease inhibitor, PI) = an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs