Enter a clue or pattern or both:

The Clue

"And what ___ rare . . . " (4 letter answer)

The Answer

ISSO

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Notes

The answer ISSO is seen occasionally, appearing about once every 750 puzzles.

Related Clues

"That ___ stupid!"
"True!"
"That ___ unfair!"
"That ___ you!"
Childish comeback
Childish rejoinder
Combative retort
Playground comeback
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"This ___ sudden"
"And what ___ rare as..."
"What ___ rare as . . . "
"And what ___ rare . . . ?": Lowell
"And what ___ rare as a day in June?"