Enter a clue or pattern or both:
The Clue
Chief artery (8 letter answer)
The Answer
MAINLINE
Tags
Notes
The answer MAINLINE is so rare that it appears less than once every 2900 puzzles.
Related Clues
Principal highway
Posh area of Phila.
Suburban Philadelphia area
It's not the road less traveled
Definition
MAINLINE as a verb:
1. inject into the vein; "She is mainlining heroin"