Enter a clue or pattern or both:

The Clue

"___ Dead?" (Mark Twain play) (4 letter answer)

The Answer

ISHE

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Notes

The answer ISHE is so rare that it appears less than once every 2500 puzzles.

Related Clues

"___ for real?" ("Can you believe that guy?")
"Who ___, Lord . . . ": John 9:36