Enter a clue or pattern or both:
The Clue
Ruffles (4 letter answer)
The Answer
IRKS
Tags
Notes
The answer IRKS is seen frequently, appearing about once every 170 puzzles.
Related Clues
Annoys
Bothers
Bugs
Exasperates
Gets to
Grates on
Irritates
Miffs
Nettles
Peeves
Piques
Unsettles
Vexes
Is vexing
Needles
Tees off
Ticks off
Tires out
Rubs the wrong way
Gets under one's skin
Definition
IRK as a verb:
1. (gall, irk) = irritate or vex; "It galls me that we lost the suit"